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VPREB3 (Pre-B Lymphocyte Protein 3, Protein VPreB3, 8HS20, N27C7-2, UNQ355/PRO619)

VPREB3 (Pre-B Lymphocyte Protein 3, Protein VPreB3, 8HS20, N27C7-2, UNQ355/PRO619)

Cat no: V2999-75

Supplier: United States Biological
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The protein encoded by this gene is the human homolog of the mouse VpreB3 (8HS20) protein, and is specifically expressed in cell lines representative of all stages of B-cell differentiation. It is also related to VPREB1 and other members of the immunoglobulin supergene family. This protein associates with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. The precise function of the protein is not known, but it may contribute to mu chain transport in pre-B cells. Applications: Suitable for use in ELISA. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2999-75
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: Pre-B Lymphocyte Gene 3
References: 1. Rosnet O, Blanco-Betancourt C, Grivel K, Richter K, Schiff C, Binding of free immunoglobulin light chains to VpreB3 inhibits their maturation and secretion in chicken B cells. The Journal of biological chemistry 2004 Mar 279 (11): 10228-36.
Additional info: Recognizes VPREB3. Species sequence homology: human, mouse, rat, porcine.

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