Home  >  Products  >  VPS29 (Vacuolar Protein Sorting-associated Protein 29, hVPS29, PEP11 Homolog, Vesicle Protein Sorting 29, DC7, DC15, MDS007)
VPS29 (Vacuolar Protein Sorting-associated Protein 29, hVPS29, PEP11 Homolog, Vesicle Protein Sorting 29, DC7, DC15, MDS007)

VPS29 (Vacuolar Protein Sorting-associated Protein 29, hVPS29, PEP11 Homolog, Vesicle Protein Sorting 29, DC7, DC15, MDS007)

Cat no: V0650-07C

Supplier: United States Biological
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VPS29 belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. It is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. VPS29 may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.1-0.3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V0650-07C
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Haft CR, de la Luz Sierra M, Bafford R, Lesniak MA, Barr VA, Taylor SI. Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes. Mol Biol Cell. 2000 Dec;11(12):4105-16. PMID: 11102511.
Additional info: Recognizes human VPS29. Species sequence homology: canine, mouse, rat.

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