Home  >  Products  >  VPS29 (Vacuolar Protein Sorting-associated Protein 29, hVPS29, PEP11 Homolog, Vesicle Protein Sorting 29, DC7, DC15, MDS007)
VPS29 (Vacuolar Protein Sorting-associated Protein 29, hVPS29, PEP11 Homolog, Vesicle Protein Sorting 29, DC7, DC15, MDS007)

VPS29 (Vacuolar Protein Sorting-associated Protein 29, hVPS29, PEP11 Homolog, Vesicle Protein Sorting 29, DC7, DC15, MDS007)

Cat no: V0650-07F

Supplier: United States Biological
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VPS29 belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. It is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. VPS29 may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Immunohistochemistry (Paraffin): 4-8ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V0650-07F
Reactivities: Human, Mouse, Rat, Canine
Hosts: Goat
Applications: ELISA, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Nakada-Tsukui K, Saito-Nakano Y, Ali V, Nozaki T. A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica. Mol Biol Cell. 2005 Nov;16(11):5294-303. Epub 2005 Aug 24.
Additional info: Recognizes human VPS29. Species sequence homology: Canine, mouse and rat.

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