Home  >  Products  >  VTI1B (Vesicle Transport Through Interaction with t-SNAREs Homolog 1B, Vesicle Transport v-SNARE Protein Vti1-like 1, Vti1-rp1, VTI1, VTI1L, VTI1L1, VTI2)
VTI1B (Vesicle Transport Through Interaction with t-SNAREs Homolog 1B, Vesicle Transport v-SNARE Protein Vti1-like 1, Vti1-rp1, VTI1, VTI1L, VTI1L1, VTI2)

VTI1B (Vesicle Transport Through Interaction with t-SNAREs Homolog 1B, Vesicle Transport v-SNARE Protein Vti1-like 1, Vti1-rp1, VTI1, VTI1L, VTI1L1, VTI2)

Cat no: V2121-80A

Supplier: United States Biological
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V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml, observed in human duodenum, kidney and testes lysates on ~26-28kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: V2121-80A
Reactivities: Human, Mouse, Rat, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: Murray RZ, Wylie FG, Khromykh T, Hume DA, Stow JL. Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha. J Biol Chem. 2005 Mar 18;280(11):10478-83. Epub 2005 Jan 7.
Additional info: Recognizes human VTI1B. Species sequence homology: Canine, mouse and rat.

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