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W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl)

W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl)

Cat no: 045390

Supplier: United States Biological
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Calmodulin antagonist. Cell proliferation inhibitor. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor. Myosin light chain kinase (MLCK) inhibitor. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 2 years after receipt when stored at -20 degrees C.
Catalogue number: 045390
Size: 5mg
Purity: >98% (NMR)
Alternative names: N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl
References: Product Reference: ?N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981) ?W-5 and quin 2-AM reverse the inhibitory effect of insulin on lipolysis due to dibutyryl cAMP: H. Goko & A. Matsuoka; Diabetes Res. Clin. Pract. 44, 101 (1999) ?Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells: A. Gulino, et al.; Cancer Res. 46, 6274 (1986) ?Hydrophobic regions function in calmodulin-enzyme(s) interactions.: T. Tanaka & H. Hidaka ; J. Biol. Chem. 255, 11078 (1980) ?

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