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WDHD1 (WD Repeat and HMG-box DNA-binding Protein 1, Acidic Nucleoplasmic DNA-binding Protein 1, And-1, And1)

WDHD1 (WD Repeat and HMG-box DNA-binding Protein 1, Acidic Nucleoplasmic DNA-binding Protein 1, And-1, And1)

Cat no: W1006-01B

Supplier: United States Biological
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This monoclonal antibody recognizes both human and mouse AND-1 (WDHD1) also known as WD repeat and HMG box DNA binding protein 1, acidic nucleoplasmic DNA-binding protein 1. AND-1 (WDHD1) is a nuclear and nucleolar protein that contains multiple WD40 repeats, and one HMG region. AND-1 (WDHD1) has a predicted molecular weight of 126kD and can form homodimers. WDHD1 is expressed in the brain, epidermis, liver, and stomach. During mitosis, AND-1 (WDHD1) is transiently expressed in nucleoplasm. AND-1 (WDHD1) can bind to DNA with high affinity and may be involved in protein-protein interactions. The role of AND-1 (WDHD1) is thought to be chromatin assembly, transcription and DNA replication. AND-1 (WDHD1) has been reported to be phosphorylated on S1041. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2ul/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: W1006-01B
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Western Blot
Size: 25ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by immunoaffinity chromatography.
References: 1. Kohler A, et al. 1997. J. Cell Sci. 110:1051.
Additional info: Recognizes AND-1. Species Crossreactivity: human and mouse.

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