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Wnt10B (Protein Wnt-10b, Protein Wnt-12, WNT12)

Wnt10B (Protein Wnt-10b, Protein Wnt-12, WNT12)

Cat no: W3038-10B

Supplier: United States Biological
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT10B is a member of the WNT family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: W3038-10B
Reactivities: Human, Mouse, Rat, Bovine, Canine
Hosts: Rabbit
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
References: 1. Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.Kem p C, Willems E, Abdo S, Lambiv L, Leyns L. Dev Dyn. 2005 Jul;233(3):1064-75. 2. Expression and regulation of WNT10B in human cancer: up-regulation of WNT10B in MCF-7 cells by beta-estradiol and down-regulation of WNT10B in NT2 cells by retinoic acid. Kirikoshi H, Katoh M. Int J Mol Med. 2002 Oct;10(4):507-11.
Additional info: Recognizes human Wnt10B. Species Crossreactivity: bovine, chimpanzee, canine, mouse, orangutan, rat.

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