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WNT4, ID (Protein Wnt-4, UNQ426/PRO864)

Cat no: W3021-01C

WNT4, ID (Protein Wnt-4, UNQ426/PRO864)

Wnt-4 belongs to the WNT family of signaling molecules that have vital roles in the development of several tissues within invertebrates and vertebrates, serving as binding ligands for frizzled family transmembrane receptors. A secreted glycoprotein, Wnt-4 is a necessary component of nephrogenesis and metacephric mesenchymal condensation. It also has been shown to be involved in unilateral uretal obstruction (UUO). Some studies suggest Wnt-4 to have a potential usefulness in the improvement of bone regeneration and restoration of craniofacial defects. Expression of Wnt-4 is wide and has been observed in kidney, adrenal gland, gonad, mammary gland, Mullerian duct, and pituitary gland. A deficiency of Wnt-4 has been implicated in causing partial female to male sex reversal, known as SERKAL syndrome. Defects in Wnt-4 expression are also causal to Rokitansky-Kuster-Hauser syndrome (RKH syndrome), which is characterized by anomalies in the genital tract of otherwise normal females.\n\nApplications: \nSuitable for use in Western Blot and Immunohistochemistry.\nOther applications not tested.\n\nRecommended Dilutions:\nWestern Blot: 2ug/ml detected WNT4 on 10ug of human testis tissue lystae\nImmunohistochemistry (Paraffin): 1:300 detected WNT4 in human testis tissue lystae\nOptimal dilutions to be determined by the researcher.\n\nRecommended Secondary Antibodies:\nI1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb\nI1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb\nI1904-46Q: IgG, H&L (HRP) Pab Gt xRb\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

W3021-01C

Size

100ug

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Rat

Form

Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.

P Type

Pab

Purity

Purified by affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human protein Wnt-4 at ~35kD. Species Crossreactivity: rat.

Read more on Supplier website

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info
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