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Products Wogonin (WOG, 5,7-Dihydroxy-8-methoxyflavone, BRN 0287152)
| Catalogue number: | 045392 |
| Size: | 5mg |
| Purity: | >98% (HPLC) |
| Alternative names: | WOG, 5,7-Dihydroxy-8-methoxyflavone, BRN 0287152 |
| References: | Product Reference: Inhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages: I. Wakabayashi; Pharmacol. Toxicol. 84, 288 (1999)? Wogonin inhibits inducible prostaglandin E(2) production in macrophages: I. Wakabayashi & K. Yasui; Eur. J. Pharmacol. 406, 477 (2000)? Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin: D.E. Shieh, et al.; Anticancer Res. 20, 2861 (2000)? Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis: R.L. Huang, et al.; Planta Med. 66, 694 (2000)? Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide: Y.C. Chen, et al.; Biochem. Pharmacol. 61, 1417 (2001)? Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells: Y.L. Chang, et al.; Mol. Pharmacol. 60, 507 (2001)? Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi: K.M. Hui, et al.; Biochem. Pharmacol. 64, 1415 (2002)? Antifungal activity of wogonin: M. Pal, et al.; Phytother. Res. 17, 1215 (2003)? Neuroprotective effect of wogonin: potential roles of inflammatory cytokines: H.Z. Piao, et al.; Arch. Pharm. Res. 27, 930 (2004)? The anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo: W. Wang, et al.; Biol. Pharm. Bull. 29, 1132 (2006)? Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis: S.C. Fas, et al.; Blood 108, 3700 (2006)? Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells: D.H. Lee, et al.; Biochem. Pharmacol. 75, 2020 (2008)? Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2: N. Lu, et al.; Life Sci. 82, 956 (2008)? Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation: H.W. Zhang, et al.; Eur. J. Pharmacol. 591, 7 (2008)? Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity: H.Z. Piao, et al.; Int. Immunopharmacol. 8, 1658 (2008)? Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells: S.T. Huang, et al.; Phytomedicine 17, 47 (2010)? Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells: J.S. Yu & A.K. Kim; Mol. Cells 31, 327 (2011)? Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9: P. Chen, et al.; Toxicology 282, 122 (2011)? Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1: G. Polier, et al.; Cell Death Dis. 2, e182 (2011)? Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway: K.F. Huang, et al.; Int. Immunopharmacol. 12, 334 (2012)? Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells: S.E. Chow, et al.; J. Cell Biochem. (Epub ahead of print) (2012)? |
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