Wogonin (WOG, 5,7-Dihydroxy-8-methoxyflavone, BRN 0287152)

Size

5mg

References

Product Reference: \nInhibitory effects of baicalein and wogonin on lipopolysaccharide-induced nitric oxide production in macrophages: I. Wakabayashi; Pharmacol. Toxicol. 84, 288 (1999)?\nWogonin inhibits inducible prostaglandin E(2) production in macrophages: I. Wakabayashi & K. Yasui; Eur. J. Pharmacol. 406, 477 (2000)?\nAntioxidant and free radical scavenging effects of baicalein, baicalin and wogonin: D.E. Shieh, et al.; Anticancer Res. 20, 2861 (2000)?\nAnti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis: R.L. Huang, et al.; Planta Med. 66, 694 (2000)?\nWogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide: Y.C. Chen, et al.; Biochem. Pharmacol. 61, 1417 (2001)?\nChinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells: Y.L. Chang, et al.; Mol. Pharmacol. 60, 507 (2001)?\nAnxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi: K.M. Hui, et al.; Biochem. Pharmacol. 64, 1415 (2002)?\nAntifungal activity of wogonin: M. Pal, et al.; Phytother. Res. 17, 1215 (2003)?\nNeuroprotective effect of wogonin: potential roles of inflammatory cytokines: H.Z. Piao, et al.; Arch. Pharm. Res. 27, 930 (2004)?\nThe anticancer activities of wogonin in murine sarcoma S180 both in vitro and in vivo: W. Wang, et al.; Biol. Pharm. Bull. 29, 1132 (2006)?\nWogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis: S.C. Fas, et al.; Blood 108, 3700 (2006)?\nRole of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells: D.H. Lee, et al.; Biochem. Pharmacol. 75, 2020 (2008)?\nWogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2: N. Lu, et al.; Life Sci. 82, 956 (2008)?\nWogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation: H.W. Zhang, et al.; Eur. J. Pharmacol. 591, 7 (2008)?\nWogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity: H.Z. Piao, et al.; Int. Immunopharmacol. 8, 1658 (2008)?\nWogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells: S.T. Huang, et al.; Phytomedicine 17, 47 (2010)?\nWogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells: J.S. Yu & A.K. Kim; Mol. Cells 31, 327 (2011)?\nInhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9: P. Chen, et al.; Toxicology 282, 122 (2011)?\nWogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1: G. Polier, et al.; Cell Death Dis. 2, e182 (2011)?\nWogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway: K.F. Huang, et al.; Int. Immunopharmacol. 12, 334 (2012)?\nWogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells: S.E. Chow, et al.; J. Cell Biochem. (Epub ahead of print) (2012)?\n