Wolf-Hirschhorn Syndrome Candidate 1-like 1 (WHSC1L1, FLJ20353, MGC126766, NSD3, pp14328)

Cat no: W0484

Supplier: United States Biological

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This gene encoding NSD3 is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. NSD3 is Histone methyltransferase which preferentially methylates 'Lys-4' and 'Lys-27' of histone H3 and is amplified in several tumor cell lines and primary breast carcinomas. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1,000-1:3,000 Optimal dilutions to be determined by the researcher. Hybridoma: F0 myeloma cells with spleen cells from BALB/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	W0484
Reactivities:	Human
Hosts:	Mouse
Applications:	ELISA, Western Blot
Size:	50ul
Form:	Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
P type:	Mab
Isotype:	IgG2b
Purity:	Purified by Protein G affinity chromatography.
References:	Angrand P.O, et al. (2001) Genomics 74(1):79-88 Stec I, et al. (2000) FEBS Lett 473(1):1-5.
Additional info:	Recognizes human NSD3.

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Wolf-Hirschhorn Syndrome Candidate 1-like 1 (WHSC1L1, FLJ20353, MGC126766, NSD3, pp14328)

Cat no: W0484

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