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WYE-687

Cat no: 022895

Supplier: United States Biological

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WYE-687 is an ATP-competitive and selective inhibitor of mammalian target of rapamycin (mTOR). Studies have shown the combination of Ras-Raf-MEK1/2 inhibitors with WYE-687 may overcome resistance to mTorKIs thus may be an effective additive therapy for treatment of patient with renal cell carcinoma or colorectal cancer.

Catalogue number:	022895
Size:	5mg
Alternative names:	Methyl 4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d] pyrimidin-6-yl)phenylcarbamate Acid;
References:	Huang, Shile., et al.: Cell Cycle, 11, 844 (2012); Yu, K., et al.: Cell Rsch., 15, 6232 (2009);

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Cat no: 022895

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