Home  >  Products  >  XAGE1 (G Antigen Family D Member 2, Cancer/Testis Antigen 12.1, CT12.1, Protein XAGE-1, XAGE1A, GAGED2, XAGE1B, XAGE1C, XAGE1D, XAGE1E)
XAGE1 (G Antigen Family D Member 2, Cancer/Testis Antigen 12.1, CT12.1, Protein XAGE-1, XAGE1A, GAGED2, XAGE1B, XAGE1C, XAGE1D, XAGE1E)

XAGE1 (G Antigen Family D Member 2, Cancer/Testis Antigen 12.1, CT12.1, Protein XAGE-1, XAGE1A, GAGED2, XAGE1B, XAGE1C, XAGE1D, XAGE1E)

Cat no: X0965-01D

Supplier: United States Biological
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XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: X0965-01D
Reactivities: Human
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Liu XF, Helman LJ, Yeung C, Bera TK, Lee B, Pastan I. XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma. Cancer Res. 2000 Sep 1;60(17):4752-5.
Additional info: Recognizes GAGED2. Species sequence homology: Human.

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