Home  >  Products  >  XC Chemokine Receptor 1 (XCR1, Chemokine XC Receptor 1, CCXCR1, G-protein Coupled Receptor 5, GPR5, Lymphotactin Receptor)
XC Chemokine Receptor 1 (XCR1, Chemokine XC Receptor 1, CCXCR1, G-protein Coupled Receptor 5, GPR5, Lymphotactin Receptor)

XC Chemokine Receptor 1 (XCR1, Chemokine XC Receptor 1, CCXCR1, G-protein Coupled Receptor 5, GPR5, Lymphotactin Receptor)

Cat no: X0989-88L

Supplier: United States Biological
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CCXCR1 is a Chemokine Receptor expressed in lymphotactin-responsive leukocyte cells. The viral macrophage inflammatory protein-II, vMIP-II (but not vMIP-I), has been found to be an antagonist of lymphotactin activity at CCXCR1. The CCXCR1 gene is located near the genes for C-C chemokine receptor 9 and SIV/HIV receptor Bonzo on chromosome 3. CCXCR1 is associated with inflammatory and immunological responses by regulating the trafficking of T and B lymphocytes and neutrophils. The up-regulation of CCXCR1 in peripheral T cells is correlated with the inflammatory process observed in Crohns disease. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 2.5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human spleen Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: X0989-88L
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Chemokine (C Motif) Receptor 1
Additional info: Recognizes human CCXCR1.

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