Home  >  Products  >  XIAP Associated Factor 1 (XIAP-associated Factor 1, XAF1, XAF-1, XIAPAF1, BIRC4-binding Protein, BIRC4BP, HSXIAPAF1)

XIAP Associated Factor 1 (XIAP-associated Factor 1, XAF1, XAF-1, XIAPAF1, BIRC4-binding Protein, BIRC4BP, HSXIAPAF1)

Cat no: X1034-29B


Supplier: United States Biological
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XAF-1 binds to XIAP, an inhibitor of caspases-3, -7, and
Catalogue number: X1034-29B
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Liston P, Fong W, Kelly NL, et al. Identification of XAF1 as an antagonist of XIAP anticaspase activity. Nature Cell Biol. 2001;3:128-33. 2. Deveraux QL, Takahashi R, Savesan GS, and Reed JC. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997;388:300-4. 3. Fong WG, Liston P, Rajcan-Separovic E, et al. Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines. Genomics 2000;70:113-122. 4. Leaman DW, Chawla-Sarkar M, Vyas K, et al. Identification of X-linked inhibitor of apoptosis associated factor-1 as an interferon-stimulated gene that augments TRAIL/Apo2L-induced apoptosis. J. Biol. Chem. 2002;277:28504-11.
Additional info: Recognizes human XAF-1 (IN).

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