Home  >  Products  >  XIAP, CT (Baculoviral IAP Repeat-containing Protein 4, E3 Ubiquitin-protein Ligase XIAP, IAP-like Protein, ILP, hILP, Inhibitor of Apoptosis Protein 3, IAP-3, hIAP-3, hIAP3, X-linked Inhibitor of Apoptosis Protein, X-linked IAP, API3, BIRC4, IAP3)

XIAP, CT (Baculoviral IAP Repeat-containing Protein 4, E3 Ubiquitin-protein Ligase XIAP, IAP-like Protein, ILP, hILP, Inhibitor of Apoptosis Protein 3, IAP-3, hIAP-3, hIAP3, X-linked Inhibitor of Apoptosis Protein, X-linked IAP, API3, BIRC4, IAP3)

Cat no: X1034-10C


Supplier: United States Biological
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Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The X- chromosome linked inhibitor of apoptosis (XIAP) contains 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases
Catalogue number: X1034-10C
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Schimmer, AD. et al. Cancer Res. 64, 7183 (2004). 2. Deveraux, QL. et al. Nature 388, 300 (1997). 3. Deveraux, QL. et al. EMBO J. 18, 5242 (1999). 4. Holcik, M. et al. 19, 4174 (2000). 5. Liston, P. et al. Nature Cell Biol. 3, 128 (2001). 6. Du, C. et al. Cell 102, 33 (2000).
Additional info: Recognizes human XIAP. Species Crossreactivity: mouse.

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