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XPA (Xeroderma pigmentosum Group A)

Cat no: X1045-07A

XPA (Xeroderma pigmentosum Group A)

Recommended Secondary Reagents: Sheep anti Rabbit IgG: HRP\n\nApplications:\nImmunohistochemistry: Paraffin. 1:50\nWestern Blotting: 1:5000\nOptimal working dilutions to be determined by researcher.\n\nImmunohistochemistry: This product does require antigen retrieval using heat treatment prior to staining of paraffin sections. We recommend the use of antigen unmasking fluid for this purpose. A two hour incubation with the antibody is recommended.

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SPECIFICATIONS

Catalog Number

X1045-07A

Size

100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Serum. Supplied as a liquid with 0.1% sodium azide.

P Type

Pab

Purity

Serum.

Isotype

IgG

References

1. Jones, C.J. and Wood, R.D. (1993). Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA. Biochemistry 32: 12096-12101.2. Li, R-Y. et al. (1998). Interactions of the Transcription/DNA rep

Additional Info

Recognizes the human DNA repair associated protein designated XPA (Xeroderma pigmentosum A).XPA is a zinc finger protein of 31kD, although it demonstrates an electophoretic mobility of 40-42kD doubled. XPA is involved in the nucleotide excision repair process. Recognizes both normal and recombinant XPA and shows no crossreactivity with other XP proteins.

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