Home  >  Products  >  Yes (c-Yes Yes1, Yes-1, Cellular Yes-1 Protein, HsT441, p61-YES, Proto-oncogene Tyrosine Protein Kinase YES, v-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1, Viral Oncogene Yes-1 Homolog 1, Yamaguchi Sarcoma Oncogene)
Yes (c-Yes Yes1, Yes-1, Cellular Yes-1 Protein, HsT441, p61-YES, Proto-oncogene Tyrosine Protein Kinase YES, v-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1, Viral Oncogene Yes-1 Homolog 1, Yamaguchi Sarcoma Oncogene)

Yes (c-Yes Yes1, Yes-1, Cellular Yes-1 Protein, HsT441, p61-YES, Proto-oncogene Tyrosine Protein Kinase YES, v-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1, Viral Oncogene Yes-1 Homolog 1, Yamaguchi Sarcoma Oncogene)

Cat no: Y2056-10

Supplier: United States Biological
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Yes is the cellular homolog of the Yamaguchi sarcoma virus oncogene. This protein has tyrosine kinase activity and belongs to the src family of proteins. Yes is closely related to thymidylate synthase (1). It promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46 (2). Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:10,000 Immunohistochemistry: 1:50-1:100 Immunocytochemistry: 1:50-1:100 Immunoprecipitation: 1:10-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: Y2056-10
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
P type: Mab
Purity: Supernatant
References: 1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1; 33: D54-8. 2. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2010)
Additional info: Recognizes human Yes at ~60kD. Species Crossreactivity: mouse, rat.

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