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YES1 (Tyrosine-protein Kinase Yes, Proto-oncogene c-Yes, p61-Yes, YES)

Cat no: Y2056-10A


Supplier: United States Biological
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Yes is the cellular homolog of the Yamaguchi sarcoma virus oncogene. This protein has tyrosine kinase activity and belongs to the src family of proteins. Yes is closely related to thymidylate synthase. It promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46. Applications: Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunofluorescence: 1:100-1:200 Western Blot: 1:500-1:3000 Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: Y2056-10A
Reactivities: Human
Hosts: Rabbit
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Size: 50ul
Form: Supplied as a liquid in PBS, pH 7.0, 1% BSA, 0.01% thimerosal, 20% glycerol.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human YES1. Species sequence homology: Rat (88%), bovine (89%), canine (98%), mouse, zebrafish (95%).

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