Home  >  Products  >  ZAP 70, phosphorylated (Tyr319) (Tyrosine-protein Kinase ZAP-70, 70kD zeta-associated Protein, Syk-related Tyrosine Kinase, SRK, ZAP70)
ZAP 70, phosphorylated (Tyr319) (Tyrosine-protein Kinase ZAP-70, 70kD zeta-associated Protein, Syk-related Tyrosine Kinase, SRK, ZAP70)

ZAP 70, phosphorylated (Tyr319) (Tyrosine-protein Kinase ZAP-70, 70kD zeta-associated Protein, Syk-related Tyrosine Kinase, SRK, ZAP70)

Cat no: Z0300-02A

Supplier: United States Biological
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ZAP70, a 70kD member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Mutations in ZAP70 gene results in a form of Severe Combined Immunodeficiency Syndrome (SCID) in humans. ZAP70 expression also defines a subset of Chronic Lymphocytic Leukemia (CLL) in patients with unmutated Ig gene and poor clinical course. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot:1:500-1:1,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: Z0300-02A
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human ZAP 70 when phosphorylated at (Tyr319). Species Cross-Reactivity: mouse, rat.

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