ZAP70 (3D2A) Antibody

Cat no: 252649

Supplier: ABBIOTEC

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Description
Additional Information

ZAP70 (Zeta-chain associated protein kinase) is a 70 kDa member of the SYK tyrosine kinase family. It plays a central role in lymphocyte activation and development, implicated in several immune disorders. ZAP70 controls TCR (T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the ZAP70 gene. ZAP70 is also e, Xenopus/Amphibian,pressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry,Porcineroviding a useful prognostic marker in patients with chronic lymphocytic leukaemia.

Catalogue number:	252649
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P43403
Antigen:	Purified recombinant fragment of human ZAP70 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3D2A4
Additional info:	Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase; SRK; ZAP70