ZBTB7B (7C12) Antibody

Cat no: 252971

Supplier: ABBIOTEC

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Description
Additional Information

ZBTB7B (Zinc finger and BTB domain-containing protein 7B) is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility comple, Xenopus/Amphibian, class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, genes.

Catalogue number:	252971
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	O15156
Antigen:	Purified recombinant fragment of human ZBTB7B e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse lgG1
Clonality:	7C12
Additional info:	Zinc finger and BTB domain-containing protein 7B; Krueppel-related zinc finger protein; cKro, Xenopus/Amphibian,; hcKro, Xenopus/Amphibian,; T-helper-inducing POZ/Krueppel-like factor; Zinc finger and BTB domain-containing protein 15; Zinc finger protein 67 homolog; ,Zebrafish/Fish,p-67; Zinc finger protein 857B; Zinc finger protein Th-POK ZBTB15; ,Zebrafish/Fish,P67; ZNF857B; ZBTB7B