ZFP91, ID (ZFP91, ZNF757, E3 ubiquitin-protein ligase ZFP91, Zinc finger protein 757, Zinc finger protein 91 homolog)

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

044071

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400(4):581-586(2010)\nJin, X., et al. J. Biol. Chem. 285(40):30539-30547(2010)\nKiem, H.P., et al. Exp. Hematol. 38(9):819-822(2010)\nSugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)\nOlsen, J.V., et al. Cell 127(3):635-648(2006)

Additional Info

Human

Alternative Names

ZFP91, ZNF757, E3 ubiquitin-protein ligase ZFP91, Zinc finger protein 757, Zinc finger protein 91 homolog