Home  >  Products  >  Zic2 (Zinc Finger Protein of the Cerebellum 2, HPE5, Odd Paired Homolog Drosophila, Zic 2, Zic Family Member 2 (Odd-paired Drosophila Homolog), Zinc Finger Protein Zic2, Zinc Finger Protein Zic-2)
Zic2 (Zinc Finger Protein of the Cerebellum 2, HPE5, Odd Paired Homolog Drosophila, Zic 2, Zic Family Member 2 (Odd-paired Drosophila Homolog), Zinc Finger Protein Zic2, Zinc Finger Protein Zic-2)

Zic2 (Zinc Finger Protein of the Cerebellum 2, HPE5, Odd Paired Homolog Drosophila, Zic 2, Zic Family Member 2 (Odd-paired Drosophila Homolog), Zinc Finger Protein Zic2, Zinc Finger Protein Zic-2)

Cat no: Z0422-01A

Supplier: United States Biological
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ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: Z0422-01A
Reactivities: Mouse
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.105 sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes a band at about 60kD in mouse brain lysate (but not in rat brain lysate). A lower band is also detected, the identity of this is unknown Species Crossreactivity: Reacts with Mouse. Predicted to react with Human (100% identity with immunogen), bovine and Zebrafish (83% identity with immunogen) due to sequence homology.

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