Home  >  Products  >  ZIPK (ZIP Kinase, ZIP, DAP-like Kinase, DLK, Death Associated Kinase 3, Death-associated Protein Kinase 3, DAP Kinase 3, DAPK 3, DAPK-3, DAPK3, EC 2.7.11.1, FLJ36473)
ZIPK (ZIP Kinase, ZIP, DAP-like Kinase, DLK, Death Associated Kinase 3, Death-associated Protein Kinase 3, DAP Kinase 3, DAPK 3, DAPK-3, DAPK3, EC 2.7.11.1, FLJ36473)

ZIPK (ZIP Kinase, ZIP, DAP-like Kinase, DLK, Death Associated Kinase 3, Death-associated Protein Kinase 3, DAP Kinase 3, DAPK 3, DAPK-3, DAPK3, EC 2.7.11.1, FLJ36473)

Cat no: Z0550-25H

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
DAPK3 (Death-associated protein kinase) is a Ca2+ calmodulin serine/threonine kinase which acts as a positive regulator of apoptosis through its catalytic activities. DAPK3 is a mediator of apoptosis and is induced by gamma interferon (1). Results suggest that DAPK3, in collaboration with Daxx and Par-4, mediates a novel nuclear pathway for apoptosis (2). It has been shown that the nuclear serine/threonine-specific kinase phosphorylates core histones H3 and H4, and myosine light chain in vitro. DAPK3 interacts with transcription and splicing factors as well as with pro-apoptotic protein Par-4 suggesting that it participates in multiple cellular processes (3). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:5000-1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: Z0550-25H
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Kawai T, et al. Mol Cell Biol 18(3):1642-51, 1998 2. Kawai T, et al. Mol Cell Biol 23(17):6174-86, 2003 3. Preuss U, et al. Nucleic Acids Res 31(3):878-85, 2003 4. Murata-Hori M, et al. FEBS Lett 451(1):81-4, 1999
Additional info: Recognizes human DAPK3.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave