Cell-permeable. A potent, selective and ATP-competitive inhibitor of c-Raf in vitro (IC50 = 70nM for inhibition of human c-Raf). Displays 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC50= 2uM).
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Catalogue number:
Z0725-20
Size:
1mg
Form:
Supplied as a white to off-white solid. Reconstitute with 100mM DMSO.