Home  >  Products  >  ZMPSTE24 (CAAX Prenyl Protease 1 Homolog, Prenyl Protein-specific Endoprotease 1, Farnesylated-proteins Converting Enzyme 1, FACE-1, Zinc Metalloproteinase Ste24 Homolog, FACE1, STE24)
ZMPSTE24 (CAAX Prenyl Protease 1 Homolog, Prenyl Protein-specific Endoprotease 1, Farnesylated-proteins Converting Enzyme 1, FACE-1, Zinc Metalloproteinase Ste24 Homolog, FACE1, STE24)

ZMPSTE24 (CAAX Prenyl Protease 1 Homolog, Prenyl Protein-specific Endoprotease 1, Farnesylated-proteins Converting Enzyme 1, FACE-1, Zinc Metalloproteinase Ste24 Homolog, FACE1, STE24)

Cat no: Z0728-50E

Supplier: United States Biological
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ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.5-1.5ug/ml, observed in human skin lysates on ~55kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: Z0728-50E
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Fong LG, Frost D, Meta M, Qiao X, Yang SH, Coffinier C, Young SG. A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria. Science. 2006 Mar 17;311(5767):1621-3. Epub 2006 Feb 16.
Additional info: Recognizes human ZMPTSE24.

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