logo
logo
ZNRF1 (E3 ubiquitin-Protein ligase, MGC101991, nerve injury-induced gene 283 Protein, nin283, peripheral nerve injury Protein nin283, ring finger Protein 42, Rnf42, zinc and ring finger 1, zinc ring finger Protein 1, zinc/RING finger Protein 1, Znrf1, Zrf

Cat no: 167542

ZNRF1 (E3 ubiquitin-Protein ligase, MGC101991, nerve injury-induced gene 283 Protein, nin283, peripheral nerve injury Protein nin283, ring finger Protein 42, Rnf42, zinc and ring finger 1, zinc ring finger Protein 1, zinc/RING finger Protein 1, Znrf1, Zrf

E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes Wallerian degeneration, a neurodegeneration disorder, by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:32,000\nWestern Blot: 1-3ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

167542

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Mouse

Form

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

P Type

Pab

Purity

Purified by ammonium sulfate precipitation.

Isotype

IgG

Additional Info

Recognizes mouse ZNRF1. Species sequence homology: Bovine, canine, human, porcine, rat.

Read more on Supplier website

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Mouse

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Rat

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Rat

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Mouse

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Rabbit

Reactivities

Rat

More info
Advertisehere
MtoZ Horizontal banner
MtoZ Biolabs

Latest promotion FROM:

MtoZ Biolabs
View promotion

Latest promotions

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...