Home  >  Products  >  ZO-1 (Tight junction protein 1, Tight junction protein ZO-1, ZO1, ZO-1, Zona Occludens 1 Protein, Zonula Occludens 1 Protein)
ZO-1 (Tight junction protein 1, Tight junction protein ZO-1, ZO1, ZO-1, Zona Occludens 1 Protein, Zonula Occludens 1 Protein)

ZO-1 (Tight junction protein 1, Tight junction protein ZO-1, ZO1, ZO-1, Zona Occludens 1 Protein, Zonula Occludens 1 Protein)

Cat no: Z0750-02F

Supplier: United States Biological
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This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:128,000 Western Blot: 0.3-1ug/ml ~170kD band observed in Human Brain (Cerebral Cortex) lysates (calculated MW of 187kD according to NP_783297.2). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: Z0750-02F
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by peptide affinity chromatography.
Alternative names: zonula occludens 1 protein, zona occludens 1, tight junction protein ZO-1, tight junction protein 1, OTTHUMP00000174520, ZO-1, MGC133289, DKFZp686M05161, tight junction protein 1 (zona occludens 1), TJP1
References: 1. Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O\1Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV, ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration.Nat. Neurosci. 2008 Apr 11 (4): 420-2
Additional info: Recognizes human ZO-1. This antibody is expected to recognize both reported isoforms (NP_003248.3; NP_783297.2).

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