A labeled metabolite of Zopiclone
Melting Point:
174-177C (dec)
Solubility:
Chloroform, Methanol
Method for Determining Identity: Proton NMR (CD3OD) spectroscopic analysis and mass spectrometric analysis.
TLC Conditions:
C18; Methanol: Water: Ammonium Hydroxide (9ml: 1ml: 5 drops). Visualized with UV and AMCS. Single spot (Rf= 0.3).
Normal Intensity:
d6 = 0.62%,
d7 = 12.42%,
d8 = 86.96%
d0, d1, d2, d3, d4, d5 = no trace
Storage and Stability:
Lyophilized powder may be stored at 4 degrees C. Stable for 6 months at 4 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Toxicity and Hazards
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