Home  >  Products  >  ZU5 (ZU5 and Death Domain Containing Inhibitor of NF-kB, ZU5 and Death Domain-containing Protein, ZUD, MGC34763, Unc-5 Homolog C (C. elegans)-like, UNC5CL)
ZU5 (ZU5 and Death Domain Containing Inhibitor of NF-kB, ZU5 and Death Domain-containing Protein, ZUD, MGC34763, Unc-5 Homolog C (C. elegans)-like, UNC5CL)

ZU5 (ZU5 and Death Domain Containing Inhibitor of NF-kB, ZU5 and Death Domain-containing Protein, ZUD, MGC34763, Unc-5 Homolog C (C. elegans)-like, UNC5CL)

Cat no: Z0893-50C

Supplier: United States Biological
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This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: Z0893-50C
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum.
References: 1. Zhang,J., Xu,L.G., Han,K.J. and Shu,H.B., Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB, J. Biol. Chem. 279 (17), 17819-17825 (2004).
Additional info: Recognizes human ZU5. Species sequence homology: chimpanzee.

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