cGMP, synthesized from GTP by both membrane-bound and soluble guanlyate cyclase enzymes, is a key intracellular second messenger molecule that transduces...
Cayman's cGMP Assay is a competitive EIA that can be used for quantification of cGMP directly obtained from cell lysates, tissue homogenates, plasma or...
cAMP is a ubiquitous cellular second messenger that is a critical component of a signal transduction pathway linking membrane receptors and their ligands to...
cAMP is a ubiquitous cellular second messenger that is a critical component of a signal transduction pathway linking membrane receptors and their ligands to...
Synthetic CBs are drug-like molecules produced to mimic the pharmacological effects of THC, the active ingredient in cannabis. Herbal smoking products, such as
CTRP3 (complement C1q TNF-related protein 3) is a glycoprotein secreted by adipocytes and leukocytes that has important roles in morphogenesis, metabolism,...
ANGPTL6 induces angiogenensis and arteriogenesis through activation of the ERK1/2-eNOS pathway. Transgenic mice that persistently overexpress ANGPTL6 have...
ANGPTL3 demonstrates pro-angiogenic effects by binding integrin (alpha)v(beta)3, which induces endothelial cell migration and adhesion. It also dually...
C1q/tumor necrosis factor 5 (CTRP5 or C1QTNF5) is a member of the C1q/tumor necrosis factor superfamily. Mutations in this gene are associated with...
Clusterin is known by many names, including apolipoprotein J (Apo-J), Up-regulated in Alzheimer's disease brain (pADHC-9), Ku70-binding protein 1 (KUB-1),...
Retinol binding protein (RBP) 4 is a vitamin A transport protein that acts as an adipokine when secreted from adipose tissue. Increased circulating RBP4...
Fat mass and obesity-associated gene (FTO) is abundantly expressed in most organs. The FTO gene product is an AlkB-like DNA/RNA demethylase with a strong...
Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the salvage pathway for the biosynthesis of nicotinamide adenine dinucleotide...
Nicotinamide phosphoribosyltransferase (Nampt) is the rate-limiting enzyme in the salvage pathway for the biosynthesis of nicotinamide adenine dinucleotide...
Fat Mass and Obesity-Associated Gene (FTO) is abundantly expressed in most organs. The gene product is an AlkB-like DNA/RNA demethylase with a strong...
Vaspin, designated as visceral adipose tissue-derived serpin A12, is an adipokine with insulin-sensitizing effects. Vaspin mRNA expression is specific for...
The COX Inhibitor Screening Assay directly measures PGF2(alpha) produced by SnCl2 reduction of COX-derived PGH2. The prostanoid product is quantified via EIA...
The COX (ovine) Inhibitor Screening Assay directly measures PGF2(alpha) produced in the cyclooxygenase reaction. The prostanoid product is quantified via EIA...
15(S)-HETE is produced from arachidonic acid by the enzyme 15-LO. In humans it is formed primarily in the respiratory epithelium, leukocytes, and...
Cayman's LTE4 EIA is a competitive assay that can be used for quantification of LTE4 in urine, plasma, serum, whole blood, as well as other heterogeneous...