Latent human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).
Latent human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).
Latent human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).
Latent human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).
Stable mutant human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).
Stable mutant human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).
A single mutation results in nearly complete loss of binding of the PAI-1 mutant to the important ligand vitronectin. All other aspects of PAI-1 biological...
A single mutation results in nearly complete loss of binding of the PAI-1 mutant to the important ligand vitronectin. All other aspects of PAI-1 biological...
This mutant contains a Ser to Cys replacement around the vitronectin binding site. Incorporation of an NBD labels allows for the reporting of binding to...
This mutant contains a Ser to Cys replacement around the vitronectin binding site. Incorporation of an NBD labels allows for the reporting of binding to...
Human PAI-1 stable mutant is reacted with an excess of human sc-tPA at physiological pH. The resulting 1:1 molar complex is purified from the remaining tPA...
Human PAI-1 stable mutant is reacted with an excess of human urokinase at physiological pH. Excess uPA is removed from the resulting 1:1 molar complex by...
This human PAI-1 variant contains a mutation at the active site to make it specific for inhibition of neutrophil elastase. Additional mutations provide...
A single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to elastase. PAI-1 is...
A single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to elastase. PAI-1 is...
A single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to Cathepsin G.
A single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to Cathepsin G.
Recombinant rat PAI-1 is the ideal choice for studies involving this animal model of fibrinolysis and cancer studies. The active fraction typically contains...
Recombinant rat PAI-1 is the ideal choice for studies involving this animal model of fibrinolysis and cancer studies. The active fraction typically contains...
Latent rat PAI-1 is a useful control for experiments when used in conjunction with the active form or stable mutant.