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The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the...
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal...
Tim-3 is a Th1-specific cell surface protein that regulates macrophage activation. It enhances the severity of autoimmune encephalomyelitis in mice. Tim-3 is...
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors,...
Thromboxane B2 (TXB2) is further metabolized enzymatically to a series of compounds, of which 11-dehydro-TXB2 is the major product found both in plasma and...
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels...
TFPI is also known as lipoprotein
TCTN3 belongs to the Tectonic protein family that regulate the Hedgehog (Hh)-signaling pathway. While the expression pattern and function of TCTN3 is not...
TCTN2 is a member of the Tectonic protein family. Tectonic proteins are transmembrane proteins that regulate the Hedgehog (Hh)-signaling pathway. Defects in...
TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most...
TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most...
Chromatin organization plays a fundamental role in regulating transcription in eukaryotic cells. The nuclear receptor corepressor (N-CoR) and silencing...
Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments...
Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments...
Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments...
Members of TRAF family associate with activated TNF-R and CD40 and have been implicated to induce nuclear translocation of NFkB. TANK can bind to all three...
Tumor necrosis factor-a (TNF-a) is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-a...
TAB1 (TAK1 binding protein 1) is an adaptor protein that can activate TAK1 in vivo through phosphorylation of TAK1, a mitogen-activated protein kinase kinase...
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is a...
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is a...
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