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United States Biological

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Paxillin (Paired Box Protein Pax-1, HuP48, PAX 1, PAX1, PXN, FLJ16691, FLJ23042, HUP48)
Paxillin (Paired Box Protein Pax-1, HuP48, PAX 1, PAX1, PXN, FLJ16691, FLJ23042, HUP48)
United States Biological

Paxillin is one of the key components of integrin signaling. Tyrosine phosphorylation of paxillin is required for integrin-mediated cytoskeletal...

Pax6 (Paired Box Protein Pax-6, Oculorhombin, Pax-6, Sey)
Pax6 (Paired Box Protein Pax-6, Oculorhombin, Pax-6, Sey)
United States Biological

PAX genes encode nuclear transcription factors that may function as major controllers of developmental processes in both vertebrates and invertebrates....

PARP, Cleaved (Poly [ADP-ribose] Polymerase 1, PARP-1, ADP-ribosyltransferase Diphtheria Toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] Synthase 1, Adprt, Parp1)
PARP, Cleaved (Poly [ADP-ribose] Polymerase 1, PARP-1, ADP-ribosyltransferase Diphtheria Toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] Synthase 1, Adprt, Parp1)
United States Biological

PARP, a 116kD nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells....

PARD3 (Partitioning Defective 3 Homolog, PAR-3, PARD-3, Atypical PKC Isotype-specific-interacting Protein, ASIP, Ephrin-interacting Protein, PHIP, Par3)
PARD3 (Partitioning Defective 3 Homolog, PAR-3, PARD-3, Atypical PKC Isotype-specific-interacting Protein, ASIP, Ephrin-interacting Protein, PHIP, Par3)
United States Biological

PARD (partitioning-defective) proteins are important in asymmetric cell division and polarized growth. PARD3 plays a vital role in the formation of...

PAK2 (Serine/Threonine-protein Kinase PAK 2, Gamma-PAK, PAK65, S6/H4 Kinase, p21-activated Kinase 2, PAK-2, p58)
PAK2 (Serine/Threonine-protein Kinase PAK 2, Gamma-PAK, PAK65, S6/H4 Kinase, p21-activated Kinase 2, PAK-2, p58)
United States Biological

The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal...

PAK1 (Serine/Threonine-protein Kinase PAK 1, Alpha-PAK, p21-activated Kinase 1, PAK-1, p65-PAK)
PAK1 (Serine/Threonine-protein Kinase PAK 1, Alpha-PAK, p21-activated Kinase 1, PAK-1, p65-PAK)
United States Biological

Human p21-GTPase-activated protein kinase 1 (PAK1) is a functional homolog of STE20 of Saccharomyces cerevisiae. PAK1 is a downstream effector of the...

p53NIDP1 (Tumor Protein p53-inducible Nuclear Protein 1, Stress-induced Protein, p53-dependent Damage-inducible Nuclear Protein 1, p53DINP1, P53DINP1, SIP)
p53NIDP1 (Tumor Protein p53-inducible Nuclear Protein 1, Stress-induced Protein, p53-dependent Damage-inducible Nuclear Protein 1, p53DINP1, P53DINP1, SIP)
United States Biological

p53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-a (27kD) and p53DINP1-b (18kD). p53DINP1 may regulate...

p53, Phosphorylated (Ser15) (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53)
p53, Phosphorylated (Ser15) (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53)
United States Biological

The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to...

p53 (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53)
p53 (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53)
United States Biological

p53, a 53kD protein, binds to a DNA consensus sequence, the p53 response element, and regulates normal cell cycle events by activating transcription of genes...

p53 (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53)
p53 (Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor Suppressor p53, TP53)
United States Biological

p53, a 53kD protein, binds to a DNA consensus sequence, the p53 response element, and regulates normal cell cycle events by activating transcription of genes...

OTX1 (Homeobox Protein OTX1, Orthodenticle Homolog 1)
OTX1 (Homeobox Protein OTX1, Orthodenticle Homolog 1)
United States Biological

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and...

Oprd1 (Delta-type Opioid Receptor, D-OR-1, DOR-1, K56, MSL-2)
Oprd1 (Delta-type Opioid Receptor, D-OR-1, DOR-1, K56, MSL-2)
United States Biological

Opioid receptors are a group of G protein coupled receptors which are used by the class of substances known as opioids. The aa sequence of the three opioid...

OMI (Serine Protease HTRA2, Mitochondrial, High Temperature Requirement Protein A2, HtrA2, Omi Stress-regulated Endoprotease, Serine Protease 25, Serine Proteinase OMI, HTRA2, PRSS25)
OMI (Serine Protease HTRA2, Mitochondrial, High Temperature Requirement Protein A2, HtrA2, Omi Stress-regulated Endoprotease, Serine Protease 25, Serine Proteinase OMI, HTRA2, PRSS25)
United States Biological

Human HtrA2 (also designated Omi) is a novel member of the HtrA serine protease family and is highly homologous to HtrA (also known as L56 and HtrA1). HtrA2...

Oct4 (POU Domain, Class 5, Transcription Factor 1, Octamer-binding Protein 3, Oct-3, Octamer-binding Protein 4, Oct-4, Octamer-binding Transcription Factor 3, OTF-3, POU5F1, OCT3, OTF3)
Oct4 (POU Domain, Class 5, Transcription Factor 1, Octamer-binding Protein 3, Oct-3, Octamer-binding Protein 4, Oct-4, Octamer-binding Transcription Factor 3, OTF-3, POU5F1, OCT3, OTF3)
United States Biological

Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and...

Nucleophosmin (NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin, NPM)
Nucleophosmin (NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin, NPM)
United States Biological

NPM (Nucleophosmin) is an abundant phosphoprotein primarily found in nucleoli. It has been implicated in several distinct cellular functions, including...

NTRK2 (TRKB, BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, Trk-B, Neurotrophic Tyrosine Kinase Receptor Type 2, TrkB Tyrosine Kinase, Tropomyosin-related Kinase B)
NTRK2 (TRKB, BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, Trk-B, Neurotrophic Tyrosine Kinase Receptor Type 2, TrkB Tyrosine Kinase, Tropomyosin-related Kinase B)
United States Biological

Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145kD,...

Nsf (Vesicle-fusing ATPase, N-ethylmaleimide-sensitive Fusion Protein, NEM-sensitive Fusion Protein, Vesicular-fusion Protein NSF, Protein SKD2, Skd2)
Nsf (Vesicle-fusing ATPase, N-ethylmaleimide-sensitive Fusion Protein, NEM-sensitive Fusion Protein, Vesicular-fusion Protein NSF, Protein SKD2, Skd2)
United States Biological

Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the...

NR1H3 (Oxysterols Receptor LXR-alpha, Liver X Receptor alpha, Nuclear Receptor Subfamily 1 Group H Member 3, LXRA)
NR1H3 (Oxysterols Receptor LXR-alpha, Liver X Receptor alpha, Nuclear Receptor Subfamily 1 Group H Member 3, LXRA)
United States Biological

Liver X receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile...

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