The sarcoplasmic reticulum of striated muscle is a specialized intracellular membrane system that plays a critical role in the contraction and relaxation of...
RRS1, also known as KIAA0112, ribosome biogenesis regulatory protein homolog, regulator of ribosome synthesis 1, ribosome biogenesis regulatory protein RRS1...
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of...
The serine/threonine kinase, p21 activated kinase (PAK), is a downstream effector of the small GTPases Cdc42 and Rac. PAK associates with Nck, the p85 and...
ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII,...
Renin is a highly specific endopeptidase that mediates the cleavage of the circulating substrate angiotensinogen to yield Angiotensin I....
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the...
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology...
The core of PDC is composed of sixty dihydrolypoyl acetyltransferase (E2) subunits that bind directly to PDK2 and enhance PDK2 kinase activity. Upregulation...
Protein Red, Cytokine IK. Function: May bind to chromatin. Tissue specificity: Ubiquitous. Sequence similarities: Belongs to the RED family. Developmental...
The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 10 (Peroxisome biogenesis factor 10), also known...
Peroxins are proteins involved in peroxisome biogenesis The peroxisome biogenesis factor Peroxin 2 (also designated Pex2) is an integral membrane protein of...
Peroxin 5 (Pex5) and Peroxin 7 (Pex7), are receptors for proteins that contain the peroxisome targeting signal 1 (PTS1) and 2 (PTS2), respectively, and...
Peroxin 5 (Pex5) and Peroxin 7 (Pex7), are receptors for proteins that contain the peroxisome targeting signal 1 (PTS1) and 2 (PTS2), respectively, and...
A farnesylated protein, Peroxin 19 (peroxisomal farnesylated protein, PxF or HK33), localizes to the outer surface of peroxisomes. Specifically, Peroxin 19...
PECI (peroxisomal D3,D2-enoyl-CoA isomerase), also known as DRS1, ACBD2 or HCA88, is a 359 amino acid protein that localizes to the peroxisomal matrix and...
Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1) and NOR-1 (neuron-derived orphan receptor-1) constitute the NGFI-B subfamily within the nuclear...
Neuromedin U (NmU) is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active...
Function: May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins. Subcellular location: Secreted. Tissue specificity: Highest...
Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Subcellular...