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A potent inhibitor of b-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly...
A potent inhibitor of serine proteases such as trypsin and chymotrypsin, and of acetylcholinesterase. Form: Colourless Liquid Boiling Point: 46 degrees C/5mm...
A potent inhibitor of Ras protein farnesyltransferase.
A potent inhibitor of Ras protein farnesyltransferase.
A potent inhibitor of cyclin-dependent kinases (CDKs). The CDKs are a family of protein kinases that are involved in the regulation of the cell cycle.
A potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases. Form: White Solid Melting Point: 153-157 degrees...
A potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Form: Off-White to Pale Yellow Solid Melting Point: 160-164 degrees...
A potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Form: Off-White Solid Melting Point: 155-157 degrees C (dec.)...
A potent hallucinogenic drug. The 5-HT2A receptor is known to act as the biologic target for a series of hallucinogenic substances including substituted...
A potent COX-2 inhibitor. Inotilone is used for treating degenerative conditions from overexpression of iNOS.
A potent competitive inhibitor of protein kinase C, cGMP-, and cAMP-dependent protein kinase with respect to ATP. Form: Off-White Solid Melting Point: >244...
A potent and selective PPARa agonist. It exhibits hypolipidemic activity in vivo. Form: Off-White Solid Melting Point: 70-76 degrees C Solubility: DMSO,...
A potent and selective orally active leukotriene A4 hydrolase inhibitor. Form: White Solid Melting Point: 163-165 degrees C Solubility: DMSO, Methanol Pfizer...
A potent and selective inhibitor of NAE. Form: White Solid Melting Point: 148-150 degrees C Solubility: Methanol
A potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying...
A possible nuclear factor kappa B inhibitor. Form: White to Off-White Solid Melting Point: 88-92 degrees C Solubility: Methanol, Water
A possible metabolite of Trazodone-HCl. Form: White Solid Melting Point: 157-159 degrees C Solubility: Methanol, Water
A possible metabolite of Brimonidine. Form: Off-White to Pale Yellow Solid Melting Point: 228-232 degrees C Solubility: Methanol
A possible fatty acyl pheromone precursors in Spodoptera littoralis
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