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5-Chloro-2-nitroanisole

Cat no: 161856


Supplier: United States Biological
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5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs. In addition it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells. Melting Point: 71-73 degrees C Solubility: Chloroform, Ethyl Acetate
Catalogue number: 161856
Size: 5g
Form: Supplied as a Yellow Solid
Alternative names: 4-Chloro-2-methoxy-1-nitrobenzene; 5-Chloro-2-nitroanisole; 1-Chloro-3-methoxy-4-nitrobenzene; 2-Methoxy-4-chloronitrobenzene; 2-Nitro-5-chloroanisole; 3-Methoxy-4-nitro-1-chlorobenzene; 4-Chloro-2-(methyloxy)-1-nitrobenzene; 4-Chloro-2-methoxy-1-nitrobenzene; 4-Chloro-2-methoxynitrobenzene; 5-Chloro-2-nitroanisole; 5-Chloro-2-nitrophenyl Methyl Ether; NSC 60112
References: Mesaros, E. et al.: J. Med. Chem., 55, 115 (2012); Diamond, M. et al.: J. Med. Chem., 50, 4939 (2007);

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