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Adipose Triglyceride Lipase Polyclonal Antibody

Cat no: 10006409

Adipose Triglyceride Lipase Polyclonal Antibody

Antigen: human adipose triglyceride lipase (ATGL) amino acids 382-400 . Host: rabbit . Cross Reactivity: (+) human, mouse, and rat ATGL . Application(s): IHC (paraffin-embedded sections) and WB . ATGL is one of the key enzymes involved in the mobilization of fatty acids from triglyceride stores in adipose tissue, catalyzing the conversion of triacylglycerols to diacylglycerols.

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SPECIFICATIONS

Catalog Number

10006409

Applications

IHC, WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Fatty Acids

Weight

0

Antigen

human adipose triglyceride lipase (ATGL) amino acids 382-400 (KRKLGRHLPSRLPEQVELR)

Storage Temp

-20

Shipping Temp

-20

Additional Info

Triglycerides are the most efficient form of energy storage in mammalian adipose tissue during times of caloric excess. ATGL is one of the key enzymes involved in the mobilization of fatty acids from triglyceride stores in adipose tissue, catalyzing the conversion of triacylglycerols to diacylglycerols. Inhibition of ATGL markedly decreases total adipose acyl-hydrolase activity, and thus may be a potential drug target for the diabetic pathology. ATGL mRNA is detected in a wide range of tissues including adipose, lung, skeletal muscle, testis, heart, brain, and kidney, with adipose tissue expressing the highest level. Human ATGL is 504 amino acids in length with an estimated molecular weight of 55.2 kDa. Cayman's ATGL polyclonal antibody detects the enzyme at 56 kDa by western blot from tissues and cells such as brown fat, liver, mouse macrophages, and HepG2 cells.

SUPPLIER INFO

Cayman Chemical Company

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