Home  >  Products  >  Adrenergic Receptor, Alpha 1B (Alpha-1B Adrenergic Receptor, Alpha-1B Adrenoceptor, Alpha-1B Adrenoreceptor, ADRA1B, ADRA1, ALPHA1BAR)

Adrenergic Receptor, Alpha 1B (Alpha-1B Adrenergic Receptor, Alpha-1B Adrenoceptor, Alpha-1B Adrenoreceptor, ADRA1B, ADRA1, ALPHA1BAR)

Cat no: A0906-50D


Supplier: United States Biological
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The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 11ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Human adrenal, medulla Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0906-50D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Adrenergic, alpha-1B-, Receptor
Additional info: Recognizes human ADRA1B. Species Crossreactivity: mouse and rat.

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