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AIF Polyclonal Antibody

Cat no: 160773

AIF Polyclonal Antibody

Antigen: human AIF amino acids 151-180 . Host: rabbit . Cross Reactivity: (+) human, rat, and mouse AIF; other species not tested . Application(s): WB . Application(s): WB . AIF is a highly conserved mitochondrial protein with roles in redox-biochemistry and apoptosis.

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SPECIFICATIONS

Catalog Number

160773

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Intracellular Signaling

Weight

0

Antigen

human AIF amino acids 151-180 (RARDPGARVLIVSEDPELPYMRPPLSKELW)

Storage Temp

-20

Shipping Temp

-20

Additional Info

Apoptosis-inducing factor (AIF) is a highly conserved mitochondrial protein with roles in redox-biochemistry and apoptosis. Apoptosis is a controlled process of cell death necessary for proper physiological development and maintenance. Loss of mitochondrial membrane potential results in the release of several proteins critical to the acceleration of apoptosis. When AIF is released from the mitochondrial intermembrane space it migrates to the nucleus to initiate chromatin condensation and DNA cleavage. AIF is recognized by immunoblotting at 67 kDa in most tissues and cell lines.

SUPPLIER INFO

Cayman Chemical Company

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