Albumin, Human Serum, Recombinant, S. cerevisiae (HSA)

Serum Albumin is a major protein in the blood. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules. Fear of infectious diseases as HIV & Hepatitis has enticed great interest in the recombinant form which is identical to the natural blood.\n\nRecombinant Human HSA is a single, non-glycosylated, polypeptide chain containing 585 amino acids and having a molecular mass of 66441 Daltons.\n\nSource: Saccharomyces Cerevisiae.\n\nDimers and Aggregates:\n(same/less than) 1% as determined by silver-stained SDS-PAGE gel analysis.\n\nApplications:\nFormulation of protein therapeutics, cell storage (cryopreservation), vaccine formulation and manufacturing, development of mammalian cell cultures, infertility treatments, coating for medical devices, drug delivery, in vivo diagnostics.\n\nEndotoxin:\n(same/less than) 0.1ng/ug (IEU/ug) of Recombinant HSA.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

A1274-94E

Size

10mg

Form

Supplied as a sterile filtered yellowish liquid containing 145mM sodium chloride, 32mM sodium octanoate and 15ug/ml Tween-80.

Purity

(same/more than) 95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.

References

1. Physicochemical characterization of cross-linked human serum albumin dimer and its synthetic heme hybrid as an oxygen carrier. Komatsu T, Oguro Y, Takeoka S, Tsuchida E, Biochim Biophys Acta 2004 Nov 18;1675 1-3:21-31 2. Application of the 19F NMR technique to observe binding of the general anesthetic halothane to human serum albumin. Shikii K, Sakurai S, Seki H, Anal Sci 2004 Oct;20(10):1475-7 3. Dioxygenation of human serum albumin having a prosthetic heme group in a tailor-made heme pocket. Komatsu T, Ohmichi N, Curry S, J Am Chem Soc 2004 Nov 10;126(44):14304-5 4. Stabilizing mechanisms in commercial albumin preparations: octanoate and N-acetyl-L-tryptophanate protect human serum albumin against heat and oxidative stress. Anraku M, Tsurusaki Y, Maruyama T, Biochim Biophys Acta 2004 Oct 1;1702(1):9-17 5. Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy. Chunfu Z, Jinquan C, Yongxian W, Appl Radiat Isot 2004 Dec;61(6):1255-9 6. Interactions of human serum albumin with chlorogenic acid and ferulic acid. Kang J, Liu Y, Li S, Biochim Biophys Acta 2004 Sep 24;1674(2):205-14.