Home  >  Products  >  Aldehyde Dehydrogenase Family 7 Member A1 (Aldh7a1, Alpha-Aminoadipic Semialdehyde Dehydrogenase, Alpha-AASA Dehydrogenase, Delta1-Piperideine-6-Carboxylate Dehydrogenease, P6c Dehydrogenase, Antiquitin-1)
Aldehyde Dehydrogenase Family 7 Member A1 (Aldh7a1, Alpha-Aminoadipic Semialdehyde Dehydrogenase, Alpha-AASA Dehydrogenase, Delta1-Piperideine-6-Carboxylate Dehydrogenease, P6c Dehydrogenase, Antiquitin-1)

Aldehyde Dehydrogenase Family 7 Member A1 (Aldh7a1, Alpha-Aminoadipic Semialdehyde Dehydrogenase, Alpha-AASA Dehydrogenase, Delta1-Piperideine-6-Carboxylate Dehydrogenease, P6c Dehydrogenase, Antiquitin-1)

Cat no: A1334-37E

Supplier: United States Biological
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Antiquitin (Aldh7a1) is an evolutionarily conserved protein believed to play a role in the regulation of cellular turgor. Based on sequence analysis, this protein is classified as a member of the aldehyde dehydrogenase superfamily (1). Analysis of the amount of mRNA in various rat and human tissues indicates that the largest amounts are found in rat kidney and liver and in cultured human hepatoma cells. Only minimal amounts were detected in human peripheral blood leukocytes, rat lung, or cultured human fibroblasts (2). The plant homolog of ATQ1 is thought to be involved in regulating turgor pressure, a function that also would be essential for cells of the mammalian cochlea. Northern blots of 13 human fetal tissues show antiquitin to be highly expressed in cochlea, ovary, eye, heart, and kidney (3). Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:50,000-100,000 Immunohistochemistry: 1:100-250 Immunocytochemistry: 1:100-250 Immunoprecipitation: 1:30 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: A1334-37E
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50 mM Tris-Glycine (pH 7.4), 0.15 M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Serum
References: 1. Tang WK, et al. FEBS Lett 516(1-3): 183-6, 2002. 2. Lee P, et al. Genomics 21(2): 371-8, 1994 3. Skvorak AB, et al. Genomics 46(2): 191-9, 1997
Additional info: Recognizes human Aldh7a1. Species Crossreactivity: mouse

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