Anti-CD8 monoclonal antibody, clone DU7 [FITC]

Cat no: DMABT-45243MG

Supplier: Creative Diagnostics

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Mouse anti-Guinea Pig CD8 monoclonal antibody for IHC, FC. CD8 is a 68 kDa disulphide-linked, transmembrane glycoprotein. The CD8 molecule serves as a receptor for MHC class I molecules and can mediate a function as a coreceptor in TCR-ligand binding and T-cell activation. Its cytoplasmic part is associated with the p56lck tyrosine kinase. CD8 is expressed by the great majority of cortical thymocytes and approximately 30% of medullary thymocytes, and by class I major histocompatibility complex restricted, mature suppressor/cytotoxic T cells. In addition a proportion of ?? T cells and NK cells express CD8. Thus, CD8 is expressed by about 25-35% of peripheral T cells, and about 30% of NK cells express low levels of CD8. Immunophenotyping of lymphocytes is widely applied as a component of the testing of peripheral blood for diagnosis of immunodeficiencies such as aquired immunodeficiency syndrome (AIDS). An increase in the percentage of CD8-positive T cells has been reported during cytomegalovirus infection.

Catalogue number:	DMABT-45243MG
Hosts:	Mouse
Clone:	DU7
Gene:	925
Target:	CD8A
Isotype:	IgG1
Clonality:	Monoclonal
Storage temp:	Store at +4 oC for one month or at -20 oC for longer.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

See Full Product Listings >

Anti-CD8 monoclonal antibody, clone DU7 [FITC]

Cat no: DMABT-45243MG

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Creative Diagnostics




By submitting this form you agree to your details being passed to Creative Diagnostics for the purpose of generating the best quote*