ApoA1 Polyclonal Antibody

Antigen: human ApoA1 protein amino acids 188-199 . Host: rabbit . Cross Reactivity: (+) human, mouse, and rat ApoA1 protein . Application(s): ICC and WB . ApoA1 is a major protein component of HDL. It acts as an acceptor for sequential transfers of phospholipids and free cholesterol from peripheral tissues and transports cholesterol to the liver and other tissues for excretion and steroidogenesis.

Prices direct from Cayman Chemical Company

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

10008463

Applications

ICC, WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

human ApoA1 protein amino acids 188-199 (RLAEYHAKATEH)

Storage Temp

-20

Shipping Temp

-20

Additional Info

ApoA1 is a major protein component in high-density lipoproteins (HDLs). It acts as an acceptor for sequential transfers of phospholipids and free cholesterol from peripheral tissues as well as transporting cholesterol to the liver and other tissues for excretion and steroidogenesis. Serum ApoA1 levels are inversely related to the risk of developing atherosclerosis. Loss-of-function mutations in ApoA1 are causes of diseases such as HDL deficiency type 1 (or Tangier disease) and type 2 (familial hypoalphalipoproteinemia), and systemic non-neuropathic amyloidosis. Liver and small intestine are two main sources of the protein. ApoA1 is comprised of a single polypeptide chain of 243 amino acid residues with an estimated molecular weight of 28 kDa. Cayman's ApoA1 Polyclonal Antibody detects the protein by WB analysis in tissue/cell samples such as liver, intestine, and HepG2 cells. The antibody can also be used for ICC.