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Products ApoA1 Polyclonal Antibody
| Catalogue number: | 10008463 |
| Hosts: | Rabbit |
| Applications: | Immunocytochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | human ApoA1 protein amino acids 188-199 (RLAEYHAKATEH) |
| P type: | Antibodies |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | ApoA1 is a major protein component in high-density lipoproteins (HDLs). It acts as an acceptor for sequential transfers of phospholipids and free cholesterol from peripheral tissues as well as transporting cholesterol to the liver and other tissues for excretion and steroidogenesis. Serum ApoA1 levels are inversely related to the risk of developing atherosclerosis. Loss-of-function mutations in ApoA1 are causes of diseases such as HDL deficiency type 1 (or Tangier disease) and type 2 (familial hypoalphalipoproteinemia), and systemic non-neuropathic amyloidosis. Liver and small intestine are two main sources of the protein. ApoA1 is comprised of a single polypeptide chain of 243 amino acid residues with an estimated molecular weight of 28 kDa. Cayman's ApoA1 Polyclonal Antibody detects the protein by WB analysis in tissue/cell samples such as liver, intestine, and HepG2 cells. The antibody can also be used for ICC. |
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