Home  >  Products  >  ARH (ARH2, DKFZp586D0624, FHCB1, FHCB2, Low Density Lipoprotein Receptor Adaptor Protein 1, MGC34705)
ARH (ARH2, DKFZp586D0624, FHCB1, FHCB2, Low Density Lipoprotein Receptor Adaptor Protein 1, MGC34705)

ARH (ARH2, DKFZp586D0624, FHCB1, FHCB2, Low Density Lipoprotein Receptor Adaptor Protein 1, MGC34705)

Cat no: A3570-65D

Supplier: United States Biological
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The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A3570-65D
Reactivities: Human
Hosts: Goat
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Alternative names: Autosomal Recessive Hypercholesterolemia Protein, LDL Receptor Adaptor Protein 1, LDLRAP1
References: He G et al. ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2. J Biol Chem 277:44044-9 (2002).
Additional info: Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse and Xenopus laevis due to sequence homology.

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