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ARL5A, aa1-179, Recombinant, Human (ADP-ribosylation Factor-like Protein 5A, ARFLP5, ARL5)

Cat no: A3570-88A

ARL5A, aa1-179, Recombinant, Human (ADP-ribosylation Factor-like Protein 5A, ARFLP5, ARL5)

ADP-ribosylation factor-like 5A, also known ARL5A, belongs to the ARF family of GTP-binding proteins. ARFs are important in eukaryotic vesicular trafficking pathways and play an essential role in the activation of phospholipase D. Unlike many ARF family members, ARL5 is thought to lack ADP-ribosylation enhancing activity. ARL5A is developmentally regulated and may play a role in nuclear dynamics and signaling cascades during embryonic development.\n\nSource:\nRecombinant corresponding to human ARL5A, fused to His-tag at N-terminus, expressed in E. coli.\n\nMolecular Weight: \n~23.3kD\n\nSequences of Amino Acids:\nMGSSHHHHHH SSGLVPRGSH MGSHMGILFT RIWRLFNHQE HKVIIVGLDN AGKTTILYQF SMNEVVHTSP TIGSNVEEIV INNTRFLMWD IGGQESLRSS WNTYYTNTEF VIVVVDSTDR ERISVTREEL YKMLAHEDLR KAGLLIFANK QDVKECMTVA EISQFLKLTS IKDHQWHIQA CCALTGEGLC QGLEWMMSRL KIR\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

A3570-88A

Size

50ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 2mM DTT, 0.2mM PMSF, 20% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Haraquchi T., et al. (2006) Biosci Biotechnol Biochem. 70:1798-1802. 2. Pasqualato S., et al. (2002) EMBO Rep. 3:1035-1041.

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