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ATXN3, ID (ATXN3, ATX3, MJD, MJD1, SCA3, Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein)

Cat no: 032319

ATXN3, ID (ATXN3, ATX3, MJD, MJD1, SCA3, Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein)

ATXN3 was known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers.\n\nApplications:\nSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\nImmunohistochemistry: 1:50-100\nFlow Cytometry: 1:10-50\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

032319

Size

200ul

Applications

ELISA, FC, IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Reina,C.P., et.al, Hum. Mol. Genet. 19 (2), 235-249 (2010)\nJung,J., et.al, Hum. Mol. Genet. 18 (24), 4843-4852 (2009)

Additional Info

Human

Alternative Names

ATXN3, ATX3, MJD, MJD1, SCA3, Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein

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