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BACE Inhibitor Screening Assay Kit

BACE Inhibitor Screening Assay Kit

Cat no: 600070

Supplier: Cayman Chemical Company
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Accumulation of the (beta)-amyloid peptide (A(beta)) in the brain is implicated as the primary cause of neurodegeneration and progression of Alzheimer's disease. BACE is a promising therapeutic target as this protease initiates the first step in A(beta) production. Cayman's BACE Inhibitor Screening Assay Kit provides a convenient method for screening human BACE inhibitors. The assay utilizes a synthetic Swedish mutant APP peptide (EVNLDAEF) that has been linked to a fluorophore (EDANS) at one end and to a quenching agent (Dabcyl) at the other. After cleavage by BACE, the product (peptide-EDANS) is brightly fluorescent with excitation and emission peaks at 335-345 nm and 485-510 nm, respectively.
Catalogue number: 600070
Weight: 0
Form: 96 Well
P type: Assay Kits
Shipping temp: -80
Storage temp: -80
Additional info: Accumulation of the (beta)-amyloid peptide (A(beta)) in the brain is implicated as the primary cause of neurodegeneration and progression of Alzheimer

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