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BAP29 (B Cell Receptor-Associated Protein 29, BCR-Associated Protein 29)

Cat no: B0076-96

BAP29 (B Cell Receptor-Associated Protein 29, BCR-Associated Protein 29)

Description:\nBap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors (3). Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins (3). Bap29 possesses multiple isoforms. \n \nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-1ug

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SPECIFICATIONS

Catalog Number

B0076-96

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.\n

P Type

Pab

Purity

Purified by immunoaffinity chromatography.\n

Isotype

IgG

References

1. Kim KM, et al.EMBO J. 1994; 13:3793-800. 2. Ng F, et al. J. Cell Biol. 1997; 139:327-38. 3. Schamel WW, et al. Proc. Natl. Acad. Sci. USA 2003; 100:9861-6. (WD0106)

Additional Info

Recognizes human BAP29. Species Crossreactivity: mouse and rat.

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