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BCL2A1 (Bcl-2-related Protein A1, Bcl-2-like Protein 5, Bcl2-L-5, Hemopoietic-specific Early Response Protein, Protein BFL-1, Protein GRS, BCL2L5, BFL1, GRS, HBPA1)

Cat no: B0807-09Y8

BCL2A1 (Bcl-2-related Protein A1, Bcl-2-like Protein 5, Bcl2-L-5, Hemopoietic-specific Early Response Protein, Protein BFL-1, Protein GRS, BCL2L5, BFL1, GRS, HBPA1)

A1 (also designated Bfl-1) is a Bcl-2 family protein that dimerizes with both Bcl-2 and Bax, and has been identified as a hematopoietic-specific, early inducible gene. Although A1 demonstrated properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and is dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. A1 expression has been correlated to stomach cancer.\n\nApplications:\nSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-4ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

B0807-09Y8

Size

100ug

Applications

IHC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

Additional Info

Recognizes human A1. Species Crossreactivity: mouse and rat.

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